Profhilo skin bio-remodelling — tissue remodelling and improvement of skin quality — Pelle Aesthetics Hertford
Aesthetic Awards — Most Innovative Treatment

Bio-Remodelling · Hertford, Hertfordshire

Profhilo®
in Hertford

The gold standard in skin bio-remodelling. Not a filler — Profhilo uses the highest concentration of pure hyaluronic acid available to deeply hydrate, tighten, and lift ageing skin from within. Administered by Dr Sabrina using the patented BAP technique.

156Five-Star Reviews
BAPPatented Technique
64mgHA Concentration
30 minTreatment Time

Rated 5.0 by 156 patients on Google. Pelle Aesthetics is Hertfordshire's top-rated doctor-led aesthetics clinic.

What is
Profhilo®?

Profhilo is a unique, award-winning bio-remodelling injectable — not a filler, not a mesotherapy treatment. It contains one of the highest concentrations of pure hyaluronic acid available (64mg/2ml), entirely free from BDDE cross-linking agents or additives.

When injected via the patented BAP protocol, Profhilo disperses through the tissue in a slow, sustained release over approximately 28 days. During this time, it stimulates four types of collagen and elastin simultaneously — producing deep hydration, genuine skin tightening, and a subtle but remarkable lifting effect on sagging tissue.

The results are not the instantaneous plumping of a filler. Instead, patients notice a progressive improvement in skin quality, firmness, and radiance over several weeks — a natural renewal that colleagues and friends notice without being able to identify.

The BAP technique,
precisely delivered

Dr Sabrina follows IBSA's own patented BAP (Bio Aesthetic Points) procedure — a protocol involving precise superficial injection into five anatomically mapped points on each side of the face. Each point is chosen to maximise the spread of Profhilo through the tissue while avoiding vascular structures.

This technique is not simply a recommendation: it is integral to Profhilo's efficacy and safety. At Pelle Aesthetics, you will never receive an improvisational approach to a treatment that has a specifically engineered protocol.

Dr Sabrina

GMC-Registered GP  ·  Founder & Lead Clinician, Pelle Aesthetics
Hertford, Hertfordshire

64mg

Hyaluronic acid per 2ml — one of the highest concentrations on the market

28 days

Slow, sustained release within the tissue after each session

4 types

Of collagen and elastin simultaneously stimulated per treatment

BDDE-free

No cross-linking agents — the purest injectable HA available

What happens
during your session

01

Consultation & Assessment

Your session begins with a skin assessment and consultation. Dr Sabrina discusses your concerns, reviews your skin laxity and hydration, and confirms Profhilo is the right treatment for your goals.

02

Skin Preparation

The treatment area is cleansed thoroughly. Topical anaesthetic is available if needed, though most patients find the BAP technique very comfortable without it.

03

BAP Injection Protocol

Dr Sabrina injects Profhilo into five precise Bio Aesthetic Points on each side of the face — the patented IBSA protocol designed to maximise tissue spread and safety.

04

Session Two (4 Weeks Later)

The standard protocol requires two sessions one month apart. After the second session, Profhilo continues working for up to 28 days, with results fully visible 4–6 weeks later.

Profhilo before and after results showing jawline tightening and skin remodelling — Pelle Aesthetics Hertford

*Courtesy of Dr Rodriguez A. Individual results may vary.

Visible tightening
& skin renewal

The before-and-after images shown demonstrate Profhilo's ability to genuinely tighten and remodel sagging tissue — particularly along the jawline, jowls, and neck. This is not volume replacement; this is structural remodelling.

Results develop progressively over 4–6 weeks following the second session, with patients typically describing improved firmness, radiance, and texture. Duration of results is 6–12 months, after which maintenance sessions sustain and build on the initial improvement.

Four types of collagen
& elastin stimulated

I

Collagen Type I

The primary structural collagen — responsible for skin strength, firmness, and resistance to sagging

III

Collagen Type III

The elasticity collagen — works alongside Type I to support skin resilience and a youthful, supple texture

IV

Collagen Type IV

The basement membrane collagen — anchors the skin layers and supports overall skin architecture

E

Elastin

The rebound protein — restores the skin's ability to spring back after movement, reducing crepiness and laxity

Three treatments,
one philosophy

This treatment

Profhilo®

The original bio-remodelling treatment for the face, neck, décolletage, and hands. The standard protocol of two sessions one month apart remains the most popular aesthetic injectable treatment in the UK.

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Extended treatment

Profhilo® Body

An adapted Profhilo formula for areas of body skin laxity — inner arms, abdomen, inner thighs, and knees. Delivers the same bio-remodelling effect where surgical options feel disproportionate.

Learn more →

Structural lifting

Profhilo® Structura

A next-generation formulation combining HA bio-remodelling with targeted structural lifting for the mid-face. Addresses volume loss and skin laxity simultaneously without traditional filler bulk.

Learn more →

Investment in your skin

Per Session

£300

face treatment — two sessions recommended one month apart

Full Course

£600

two sessions (the standard protocol) — enquire about course pricing

Additional Areas

Bespoke

neck, décolletage, and hands — pricing discussed at consultation

Treatment summary

Treatment Time

~30 minutes

Return to Work

Immediate

Recovery

Up to 24 hours

Sessions

2 (one month apart)

Results Visible

After 2nd session

Duration

6–12 months

Frequently asked questions

Profhilo is a BDDE-free injectable bio-remodelling treatment with one of the highest concentrations of pure hyaluronic acid on the market — 64mg per 2ml. Unlike fillers, it does not add structural volume. Instead, it disperses through the skin via a slow, sustained release over approximately 28 days, stimulating four types of collagen and elastin for deep hydration, lifting, and tightening of sagging tissue.
No — Profhilo is not a filler. It contains no BDDE cross-linking agent and is not designed to add structural volume or reshape facial contours. It is a bio-remodelling treatment: the ultra-pure hyaluronic acid spreads through the tissue and stimulates the skin's own regenerative processes, producing a tightening and lifting effect from within rather than from additional volume.
BAP stands for Bio Aesthetic Points — a patented injection protocol developed specifically for Profhilo by IBSA. It involves precise superficial injection into five anatomically defined points on each side of the face, carefully mapped to maximise the spread of Profhilo through the tissue while avoiding vascular structures. Dr Sabrina follows this protocol exactly as intended.
The standard protocol is two sessions, four weeks apart. Some patients may benefit from a third session for optimal results. Maintenance sessions every 6–12 months are recommended to sustain and build on the remodelling effect.
Profhilo can be used on the face, neck, décolletage, and hands. There are also dedicated variants for body skin laxity (Profhilo Body — inner arms, abdomen, thighs, knees) and structural mid-face lifting (Profhilo Structura). Dr Sabrina can advise on the most appropriate treatment or combination at consultation.
Profhilo is one of the safest injectable treatments available. It is entirely free from BDDE cross-linkers and additives. Possible side effects are mild and temporary — including small injection-site bumps (which resolve within 24 hours), mild swelling, and bruising. Rare risks including infection and allergic reaction are discussed in full at your consultation before any treatment proceeds.